Naproxen sodium has several contraindications and interactions that should be considered before taking the medication.

Contraindications:

Naproxen sodium should not be taken by people who are allergic to naproxen or any other ingredient in the medication.
It should not be taken by people with a history of stomach ulcers, bleeding, or a history of bleeding disorders.
It should also not be taken by people with a history of kidney disease or liver disease.
It should not be taken by women who are pregnant or breastfeeding.

Drug Interactions:

Naproxen sodium can interact with other medications, including blood-thinning medications (such as warfarin), aspirin, and other NSAIDs. Taking naproxen sodium with these medications can increase the risk of stomach bleeding and other side effects.
It can also interact with diuretics, lithium, and methotrexate, leading to an increased risk of side effects.
People who are taking other medications should inform their healthcare provider before taking naproxen sodium to ensure that it is safe to take and to avoid any potential drug interactions.
It is important to use naproxen sodium exactly as directed by a healthcare provider and to be aware of any potential contraindications and interactions. If you have any questions or concerns about using naproxen sodium, it is best to consult with a healthcare provider.